Clofibrate

CHEMBL565 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

242.7 g/mol

LogP

3.3

Phase

4

A fibric acid derivative that lowers blood triglycerides and raises HDL cholesterol by activating PPAR-alpha receptors in the liver. Its use has largely been replaced by newer fibrates due to concerns about serious side effects including gallstones and muscle toxicity.

Moleküler Ağırlık

242,7000 g/mol

LogP

3,30

TPSA

35,50 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Cardiovascular Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1

InChI

InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

Molecular Formula

C12H15ClO3

HBD / HBA

- / 3

Döndürülebilir Bağlar

5

Ağır Atomlar

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A fibric acid derivative that lowers blood triglycerides and raises HDL cholesterol by activating PPAR-alpha receptors in the liver. Its use has largely been replaced by newer fibrates due to concerns about serious side effects including gallstones and muscle toxicity.

Yes, Clofibrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL565. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2796. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Formül: C12H15ClO3

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.