Cloxacillin

CHEMBL891 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

435.9 g/mol

LogP

2.4

Phase

4

A penicillinase-resistant penicillin antibiotic used to treat infections caused by staphylococci that produce beta-lactamase enzymes. It works by inhibiting bacterial cell wall synthesis and is taken orally on an empty stomach for best absorption.

Moleküler Ağırlık

435,9000 g/mol

LogP

2,40

TPSA

138,00 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Infectious Disease Chronic Kidney Disease Breast Cancer Atopic Dermatitis Prostate Cancer Colorectal Cancer

Etki Mekanizması

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell …

2D Yapı

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SMILES

Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O

InChI

InChI=1S/C19H18ClN3O5S/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27)/t13-,14+,17-/m1/s1

Molecular Formula

C19H18ClN3O5S

HBD / HBA

2 / 7

Döndürülebilir Bağlar

4

Ağır Atomlar

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A penicillinase-resistant penicillin antibiotic used to treat infections caused by staphylococci that produce beta-lactamase enzymes. It works by inhibiting bacterial cell wall synthesis and is taken orally on an empty stomach for best absorption.

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Yes, Cloxacillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL891. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6098. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Hızlı Veriler

Formül: C19H18ClN3O5S
Eş Anlamlılar: 2

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.