Deserpidine

CHEMBL1200515 Phase 4 Onaylandı Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
578.7 g/mol
LogP
4.1
Phase
4

A rauwolfia alkaloid that depletes catecholamine and serotonin stores in nerve terminals, used historically to treat high blood pressure and certain psychiatric conditions. Like reserpine, it can cause severe depression as a side effect. Its use has been largely abandoned in favor of safer and more effective antihypertensives.

Moleküler Ağırlık

578,7000 g/mol

LogP

4,10

TPSA

109,00 Ų

Lipinski RO5

Geçer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5ccccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC

InChI

InChI=1S/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1

Molecular Formula

C32H38N2O8

HBD / HBA

1 / 9

Döndürülebilir Bağlar

9

Ağır Atomlar

42

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A rauwolfia alkaloid that depletes catecholamine and serotonin stores in nerve terminals, used historically to treat high blood pressure and certain psychiatric conditions. Like reserpine, it can cause severe depression as a side effect. Its use has been largely abandoned in favor of safer and more effective antihypertensives.

Yes, Deserpidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200515. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 8550. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.