Dobutamine

CHEMBL926 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

301.4 g/mol

LogP

3.4

Phase

4

A synthetic catecholamine used intravenously to treat acute heart failure and cardiogenic shock by stimulating beta-1 adrenergic receptors in the heart, increasing the strength of cardiac contractions and improving cardiac output. It is also used in pharmacological cardiac stress testing (dobutamine stress echocardiography). It can cause increased heart rate and must be used with continuous cardiac monitoring.

Moleküler Ağırlık

301,4000 g/mol

LogP

3,40

TPSA

72,70 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Bladder Cancer Cardiovascular Disease Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Chronic Kidney Disease Hypertension Breast Cancer Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

Cite this structure

Embed this structure

SMILES

CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1

InChI

InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3

Molecular Formula

C18H23NO3

HBD / HBA

4 / 4

Döndürülebilir Bağlar

7

Ağır Atomlar

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A synthetic catecholamine used intravenously to treat acute heart failure and cardiogenic shock by stimulating beta-1 adrenergic receptors in the heart, increasing the strength of cardiac contractions and improving cardiac output. It is also used in pharmacological cardiac stress testing (dobutamine stress echocardiography). It can cause increased heart rate and must be used with continuous cardiac monitoring.

Yes, Dobutamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL926. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 36811. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Hızlı Veriler

Formül: C18H23NO3
Eş Anlamlılar: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.