Isoproterenol Hydrochloride

CHEMBL1711 Phase 4 Onaylandı Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
247.7 g/mol
LogP
Phase
4

This hydrochloride salt of isoproterenol is the standard injectable form used in acute care settings for cardiac emergencies such as symptomatic bradycardia and heart block while awaiting pacemaker placement. It also has bronchodilatory properties and has historically been used for asthma. Its potent cardiac effects require continuous monitoring during use.

Moleküler Ağırlık

247,7200 g/mol

TPSA

72,70 Ų

Terapötik Alanlar

Etki Mekanizması

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

2D Yapı

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SMILES

CC(C)NCC(O)c1ccc(O)c(O)c1.Cl

InChI

InChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

Molecular Formula

C11H18ClNO3

HBD / HBA

5 / 4

Döndürülebilir Bağlar

4

Ağır Atomlar

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

This hydrochloride salt of isoproterenol is the standard injectable form used in acute care settings for cardiac emergencies such as symptomatic bradycardia and heart block while awaiting pacemaker placement. It also has bronchodilatory properties and has historically been used for asthma. Its potent cardiac effects require continuous monitoring during use.

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Yes, Isoproterenol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1711. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5807. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.