Lenacapavir

CHEMBL4594438 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

968.3 g/mol

LogP

6.4

Phase

4

A first-in-class HIV-1 capsid inhibitor used to treat multidrug-resistant HIV infection in combination with other antiretrovirals. It works at multiple stages of the viral life cycle by disrupting the protein shell that protects HIV's genetic material.

Moleküler Ağırlık

968,3000 g/mol

LogP

6,40

TPSA

175,00 Å²

Lipinski RO5

Başarısız

Terapötik Alanlar

HIV/AIDS

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

Cite this structure

Embed this structure

SMILES

CC(C)(C#Cc1ccc(-c2ccc(Cl)c3c(NS(C)(=O)=O)nn(CC(F)(F)F)c23)c([C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2C(F)(F)[C@@H]2C[C@H]32)n1)S(C)(=O)=O

InChI

InChI=1S/C39H32ClF10N7O5S2/c1-36(2,63(3,59)60)10-9-21-5-6-22(23-7-8-26(40)30-32(23)57(17-37(43,44)45)54-35(30)55-64(4,61)62)31(51-21)27(13-18-11-19(41)14-20(42)12-18)52-28(58)16-56-34-29(33(53-56)39(48,49)50)24-15-25(24)38(34,46)47/h5-8,11-12,14,24-25,27H,13,15-17H2,1-4H3,(H,52,58)(H,54,55)/t24-,25+,27-/m0/s1

Molecular Formula

C39H32ClF10N7O5S2

HBD / HBA

2 / 19

Döndürülebilir Bağlar

13

Ağır Atomlar

64

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A first-in-class HIV-1 capsid inhibitor used to treat multidrug-resistant HIV infection in combination with other antiretrovirals. It works at multiple stages of the viral life cycle by disrupting the protein shell that protects HIV's genetic material.

Yes, Lenacapavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594438. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 133082658. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Hızlı Veriler

Formül: C39H32ClF10N7O5S2
Eş Anlamlılar: 2

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Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.