Pirprofen

CHEMBL188952 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

251.7 g/mol

LogP

2.9

Phase

4

Pirprofen is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and fever. It was used for the treatment of rheumatic and inflammatory conditions but was withdrawn due to hepatotoxicity concerns.

Moleküler Ağırlık

251,7100 g/mol

LogP

2,90

TPSA

40,50 Å²

Lipinski RO5

Geçer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

CC(C(=O)O)c1ccc(N2CC=CC2)c(Cl)c1

InChI

InChI=1S/C13H14ClNO2/c1-9(13(16)17)10-4-5-12(11(14)8-10)15-6-2-3-7-15/h2-5,8-9H,6-7H2,1H3,(H,16,17)

Molecular Formula

C13H14ClNO2

HBD / HBA

1 / 3

Döndürülebilir Bağlar

3

Ağır Atomlar

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

Pirprofen is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and fever. It was used for the treatment of rheumatic and inflammatory conditions but was withdrawn due to hepatotoxicity concerns.

Yes, Pirprofen is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL188952. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 35935. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Formül: C13H14ClNO2

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.