Quinupristin
An antibiotic used in combination with dalfopristin to treat serious infections caused by certain gram-positive bacteria, including vancomycin-resistant strains. It works by blocking bacterial protein synthesis at two different points, making it difficult for bacteria to develop resistance.
Moleküler Ağırlık
1022,2000 g/mol
LogP
4,20
TPSA
257,00 Ų
Lipinski RO5
Başarısız
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Yapı
Cite this structure
Embed this structure
SMILES
CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2CC(=O)[C@H](CS[C@@H]3CN4CCC3CC4)CN2C(=O)[C@H](Cc2ccc(N(C)C)cc2)N(C)C(=O)[C@@H]2CCCN2C1=O
InChI
InChI=1S/C53H67N9O10S/c1-6-37-50(68)61-23-11-14-38(61)51(69)59(5)40(26-32-16-18-36(19-17-32)58(3)4)52(70)62-28-35(30-73-43-29-60-24-20-33(43)21-25-60)42(64)27-39(62)47(65)57-45(34-12-8-7-9-13-34)53(71)72-31(2)44(48(66)55-37)56-49(67)46-41(63)15-10-22-54-46/h7-10,12-13,15-19,22,31,33,35,37-40,43-45,63H,6,11,14,20-21,23-30H2,1-5H3,(H,55,66)(H,56,67)(H,57,65)/t31-,35+,37-,38+,39+,40+,43-,44+,45+/m1/s1
Molecular Formula
C53H67N9O10S
HBD / HBA
4 / 14
Döndürülebilir Bağlar
10
Ağır Atomlar
73
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
An antibiotic used in combination with dalfopristin to treat serious infections caused by certain gram-positive bacteria, including vancomycin-resistant strains. It works by blocking bacterial protein synthesis at two different points, making it difficult for bacteria to develop resistance.
Yes, Quinupristin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200649. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5388937. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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