Sulfamethazine

CHEMBL446 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

278.3 g/mol

LogP

0.3

Phase

4

Sulfamethazine (sulfadimidine) is an intermediate-acting sulfonamide antibiotic used in veterinary medicine and historically in human medicine for treatment of urinary tract infections, respiratory infections, and meningitis caused by susceptible bacteria. It inhibits dihydropteroate synthase, blocking folic acid synthesis in susceptible organisms. It is primarily used today in veterinary practice due to sulfonamide resistance and availability of superior human antibiotics.

Moleküler Ağırlık

278,3300 g/mol

LogP

0,30

TPSA

106,00 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Age-Related Macular Degeneration Respiratory Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Psoriasis Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Obesity Lymphoma Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain HIV/AIDS Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

Cite this structure

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SMILES

Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1

InChI

InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

Molecular Formula

C12H14N4O2S

HBD / HBA

2 / 6

Döndürülebilir Bağlar

3

Ağır Atomlar

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

Sulfamethazine (sulfadimidine) is an intermediate-acting sulfonamide antibiotic used in veterinary medicine and historically in human medicine for treatment of urinary tract infections, respiratory infections, and meningitis caused by susceptible bacteria. It inhibits dihydropteroate synthase, blocking folic acid synthesis in susceptible organisms. It is primarily used today in veterinary practice due to sulfonamide resistance and availability of superior human antibiotics.

Yes, Sulfamethazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL446. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5327. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Hızlı Veriler

Formül: C12H14N4O2S
Eş Anlamlılar: 8

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.