Tamoxifen
This medication blocks estrogen receptors in breast tissue and is widely used to treat and reduce the risk of hormone receptor-positive breast cancer in both women and men. It is typically taken as a daily tablet for five to ten years as part of a long-term cancer prevention or treatment plan. Regular gynecologic check-ups are recommended because it can have estrogen-like effects on the uterus.
Moleküler Ağırlık
371,5150 g/mol
LogP
7,10
TPSA
12,50 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
İlaç Sınıfları
Etki Mekanizması
Selective estrogen receptor modulator (SERM).
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selective estrogen receptor modulator (SERM).
2D Yapı
Cite this structure
Embed this structure
SMILES
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
InChI
InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
Molecular Formula
C26H29NO
HBD / HBA
- / 2
Döndürülebilir Bağlar
8
Ağır Atomlar
28
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This medication blocks estrogen receptors in breast tissue and is widely used to treat and reduce the risk of hormone receptor-positive breast cancer in both women and men. It is typically taken as a daily tablet for five to ten years as part of a long-term cancer prevention or treatment plan. Regular gynecologic check-ups are recommended because it can have estrogen-like effects on the uterus.
Selective estrogen receptor modulator (SERM).
Key pharmacokinetic parameters for Tamoxifen: Half-life: 5-7 days.
Yes, Tamoxifen is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
Same Drug Class
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL83. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2733526. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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