Technetium Tc 99M Exametazime
Technetium Tc 99m exametazime (99mTc-HMPAO) is a lipophilic radiopharmaceutical used for cerebral perfusion SPECT imaging and radiolabeling of leukocytes for infection/inflammation detection. See technetium-exametazime for complete pharmacological details. It is widely used in nuclear medicine for neurological and inflammatory disease evaluation.
Moleküler Ağırlık
384,2700 g/mol
TPSA
87,10 Ų
Etki Mekanizması
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
SMILES
C[C@H](/C(=N/O)/C)[N-]CC(C)(C)C[N-][C@H](C)/C(=N/[O-])/C.O=[99Tc+3]
InChI
InChI=1S/C13H26N4O2.O.Tc/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19;;/h9-10,18-19H,7-8H2,1-6H3;;/q-2;;+3/p-1/b16-11+,17-12+;;/t9-,10-;;/m1../s1/i;;1+1
Molecular Formula
C13H25N4O3Tc
HBD / HBA
1 / 7
Döndürülebilir Bağlar
8
Ağır Atomlar
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
Technetium Tc 99m exametazime (99mTc-HMPAO) is a lipophilic radiopharmaceutical used for cerebral perfusion SPECT imaging and radiolabeling of leukocytes for infection/inflammation detection. See technetium-exametazime for complete pharmacological details. It is widely used in nuclear medicine for neurological and inflammatory disease evaluation.
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Yes, Technetium Tc 99M Exametazime is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107074. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 11954234. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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