Lead Optimization

Research

The medicinal chemistry process of modifying a lead compound to improve potency, selectivity, ADME properties, and safety while maintaining drug-likeness. Iterative design-make-test-analyze cycles.

Örnekler

Improving metabolic stability
Reducing hERG liability
Enhancing oral bioavailability

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The medicinal chemistry process of modifying a lead compound to improve potency, selectivity, ADME properties, and safety while maintaining drug-likeness. Iterative design-make-test-analyze cycles.