Amlodipine vs Sildenafil

## Amlodipine vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Amlodipine** and **Sildenafil**.

## Mechanism of Action

**Amlodipine**: Dihydropyridine calcium channel blocker.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Amlodipine — 30-50 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Amlodipine — C20H25ClN2O5; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Amlodipine — 408.8800 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Amlodipine — Small molecule; Sildenafil — Small molecule.