Atezolizumab vs Gefitinib

## Atezolizumab vs Gefitinib: Overview

This comparison examines the pharmacological differences between **Atezolizumab** and **Gefitinib**.

## Mechanism of Action

**Atezolizumab**: Fully human anti-PD-L1 IgG1 monoclonal antibody blocking PD-L1 interaction with PD-1 and B7.1.

**Gefitinib**: Selective reversible inhibitor of EGFR tyrosine kinase.

## Pharmacokinetics

**Half-life**: Atezolizumab — 27 days; Gefitinib — 48 hours.

## Chemical Properties

**Molecular Formula**: Atezolizumab — N/A; Gefitinib — C22H24ClFN4O3.

**Molecular Weight**: Atezolizumab — N/A; Gefitinib — 446.9000 g/mol.

**Type**: Atezolizumab — Antibody; Gefitinib — Small molecule.