Captopril vs Dapagliflozin

## Captopril vs Dapagliflozin: Overview

This comparison examines the pharmacological differences between **Captopril** and **Dapagliflozin**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Dapagliflozin**: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Dapagliflozin — 12.9 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Dapagliflozin — C21H25ClO6.

**Molecular Weight**: Captopril — 217.2850 g/mol; Dapagliflozin — 408.8730 g/mol.

**Type**: Captopril — Small molecule; Dapagliflozin — Small molecule.