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Alfuzosin

CHEMBL709 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
389.4 g/mol
LogP
1.7
Phase
4

An alpha-1 adrenergic blocker that relaxes the muscles of the prostate and bladder neck, making it easier to urinate in men with benign prostatic hyperplasia (BPH). It improves urinary flow and reduces symptoms such as incomplete bladder emptying, frequent urination, and nighttime awakenings to urinate.

Khối lượng phân tử

389,4000 g/mol

LogP

1,70

TPSA

112,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Benign Prostatic Hyperplasia Cardiovascular Disease Respiratory Disease Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC

                

                

                
                

                    
InChI

                    
InChI=1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23)

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H27N5O4

                    

                    
                    

                        
HBD / HBA

                        
2 / 8

                    

                    
                    

                        
Liên kết có thể quay

                        
8

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
28

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
An alpha-1 adrenergic blocker that relaxes the muscles of the prostate and bladder neck, making it easier to urinate in men with benign prostatic hyperplasia (BPH). It improves urinary flow and reduces symptoms such as incomplete bladder emptying, frequent urination, and nighttime awakenings to urinate.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Alfuzosin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL709.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2092.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.