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Amlodipine Maleate

CHEMBL1200984 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
524.9 g/mol
LogP
—
Phase
4

The maleate salt of amlodipine that delivers the same blood pressure-lowering and vessel-relaxing effects as other formulations. It blocks calcium from entering smooth muscle cells in vessel walls, reducing resistance to blood flow.

Khối lượng phân tử

524,9000 g/mol

TPSA

174,00 Ų

Lĩnh vực điều trị

Ovarian Cancer Cardiovascular Disease Chronic Obstructive Pulmonary Disease Alzheimer's Disease Generalized Anxiety Disorder Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hyperlipidemia Obesity Type 2 Diabetes Hypertension Breast Cancer HIV/AIDS Hepatitis C Heart Failure Atrial Fibrillation

Cơ chế tác dụng

Dihydropyridine calcium channel blocker.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Dihydropyridine calcium channel blocker.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.O=C(O)/C=C\C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C20H25ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8,17,23H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H29ClN2O9

                    

                    
                    

                        
HBD / HBA

                        
4 / 11

                    

                    
                    

                        
Liên kết có thể quay

                        
12

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
36

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
The maleate salt of amlodipine that delivers the same blood pressure-lowering and vessel-relaxing effects as other formulations. It blocks calcium from entering smooth muscle cells in vessel walls, reducing resistance to blood flow.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Dihydropyridine calcium channel blocker.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Amlodipine Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200984.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 6435922.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.