Amodiaquine

CHEMBL682 Phase 4 Đã phê duyệt Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
355.9 g/mol
LogP
2.6
Phase
4

An antimalarial drug that interferes with the parasite's ability to process a toxic byproduct of hemoglobin digestion, leading to the parasite's death. It is sometimes used in combination therapies for malaria and has been studied for activity against HIV.

Khối lượng phân tử

355,9000 g/mol

LogP

2,60

TPSA

48,40 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

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SMILES

CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O

InChI

InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)

Molecular Formula

C20H22ClN3O

HBD / HBA

2 / 4

Liên kết có thể quay

6

Nguyên tử nặng

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

An antimalarial drug that interferes with the parasite's ability to process a toxic byproduct of hemoglobin digestion, leading to the parasite's death. It is sometimes used in combination therapies for malaria and has been studied for activity against HIV.

Yes, Amodiaquine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL682. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2165. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.