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Berberine

CHEMBL295124 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
336.4 g/mol
LogP
3.6
Phase
4

A plant-derived alkaloid found in several herbs, with evidence suggesting benefits for blood sugar control, cholesterol levels, and gut health. It activates a key enzyme involved in energy metabolism, similar in some ways to metformin. It is used as a dietary supplement and in traditional medicine.

Khối lượng phân tử

336,4000 g/mol

LogP

3,60

TPSA

40,80 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Schizophrenia Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Hyperlipidemia Obesity Type 2 Diabetes Hypertension Hepatitis C Cardiovascular Disease Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1ccc2cc3[n+](cc2c1OC)CCc1cc2c(cc1-3)OCO2

                

                

                
                

                    
InChI

                    
InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H18NO4+

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
2

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A plant-derived alkaloid found in several herbs, with evidence suggesting benefits for blood sugar control, cholesterol levels, and gut health. It activates a key enzyme involved in energy metabolism, similar in some ways to metformin. It is used as a dietary supplement and in traditional medicine.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Berberine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL295124.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2353.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.