Biotin

CHEMBL857 Phase 4 Đã phê duyệt Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
244.3 g/mol
LogP
0.3
Phase
4

A water-soluble B vitamin essential for enzymes involved in fat, carbohydrate, and protein metabolism. It is used to treat or prevent biotin deficiency and is found in many nutritional supplements marketed for hair, skin, and nail health. True deficiency is rare but can occur with prolonged raw egg white consumption or certain inherited metabolic disorders.

Khối lượng phân tử

244,3100 g/mol

LogP

0,30

TPSA

104,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Cơ chế tác dụng

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Cấu trúc 2D

SVG PNG

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SMILES

O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

InChI

InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

Molecular Formula

C10H16N2O3S

HBD / HBA

3 / 4

Liên kết có thể quay

5

Nguyên tử nặng

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

A water-soluble B vitamin essential for enzymes involved in fat, carbohydrate, and protein metabolism. It is used to treat or prevent biotin deficiency and is found in many nutritional supplements marketed for hair, skin, and nail health. True deficiency is rare but can occur with prolonged raw egg white consumption or certain inherited metabolic disorders.

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Yes, Biotin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL857. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 171548. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.