Cannabidiol
A non-psychoactive cannabinoid derived from the cannabis plant, approved in purified oral form for treating seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. It is thought to exert anticonvulsant effects through several mechanisms, including modulation of ion channels and inhibition of endocannabinoid reuptake. It is also widely used as an unregulated supplement for anxiety, pain, and sleep, though clinical evidence varies.
Khối lượng phân tử
314,5000 g/mol
LogP
6,50
TPSA
40,50 Ų
Lipinski RO5
Đạt
Lĩnh vực điều trị
Cơ chế tác dụng
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O
InChI
InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1
Molecular Formula
C21H30O2
HBD / HBA
2 / 2
Liên kết có thể quay
6
Nguyên tử nặng
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
A non-psychoactive cannabinoid derived from the cannabis plant, approved in purified oral form for treating seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. It is thought to exert anticonvulsant effects through several mechanisms, including modulation of ion channels and inhibition of endocannabinoid reuptake. It is also widely used as an unregulated supplement for anxiety, pain, and sleep, though clinical evidence varies.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Cannabidiol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL190461. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 644019. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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