Chloroprocaine Hydrochloride
The hydrochloride salt formulation of chloroprocaine is the clinical preparation used for epidural and infiltration anesthesia. It shares the rapid onset and short duration of action of the parent compound due to fast ester hydrolysis. It is favored in labor analgesia and ambulatory surgical settings.
Khối lượng phân tử
307,2100 g/mol
TPSA
55,60 Ų
Lĩnh vực điều trị
Cơ chế tác dụng
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCN(CC)CCOC(=O)c1ccc(N)cc1Cl.Cl
InChI
InChI=1S/C13H19ClN2O2.ClH/c1-3-16(4-2)7-8-18-13(17)11-6-5-10(15)9-12(11)14;/h5-6,9H,3-4,7-8,15H2,1-2H3;1H
Molecular Formula
C13H20Cl2N2O2
HBD / HBA
2 / 4
Liên kết có thể quay
7
Nguyên tử nặng
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
The hydrochloride salt formulation of chloroprocaine is the clinical preparation used for epidural and infiltration anesthesia. It shares the rapid onset and short duration of action of the parent compound due to fast ester hydrolysis. It is favored in labor analgesia and ambulatory surgical settings.
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Yes, Chloroprocaine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL944. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 441348. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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