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Cholic Acid

CHEMBL205596 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
408.6 g/mol
LogP
3.6
Phase
4

A primary bile acid that facilitates the absorption of dietary fats and fat-soluble vitamins in the small intestine by emulsifying lipid droplets. It is used therapeutically to treat inborn errors of bile acid synthesis, rare metabolic disorders that impair the body's ability to produce bile acids naturally. Oral replacement with cholic acid helps restore normal bile flow and prevents progressive liver damage.

Khối lượng phân tử

408,6000 g/mol

LogP

3,60

TPSA

98,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Rheumatoid Arthritis Gastroesophageal Reflux Disease Non-Alcoholic Fatty Liver Disease Hyperlipidemia Obesity Type 2 Diabetes Breast Cancer Atopic Dermatitis HIV/AIDS Hepatitis C Heart Failure Cardiovascular Disease Colorectal Cancer Leukemia

Cơ chế tác dụng

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

                

                

                
                

                    
InChI

                    
InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H40O5

                    

                    
                    

                        
HBD / HBA

                        
4 / 5

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A primary bile acid that facilitates the absorption of dietary fats and fat-soluble vitamins in the small intestine by emulsifying lipid droplets. It is used therapeutically to treat inborn errors of bile acid synthesis, rare metabolic disorders that impair the body's ability to produce bile acids naturally. Oral replacement with cholic acid helps restore normal bile flow and prevents progressive liver damage.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Cholic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL205596.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 221493.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.