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Clomipramine

CHEMBL415 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
314.9 g/mol
LogP
5.2
Phase
4

A tricyclic antidepressant with particularly strong serotonin-reuptake inhibition, making it the most effective pharmacological treatment for obsessive-compulsive disorder. It also has uses in treating depression, panic disorder, and chronic pain.

Khối lượng phân tử

314,9000 g/mol

LogP

5,20

TPSA

6,50 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Schizophrenia Generalized Anxiety Disorder Major Depressive Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc21

                

                

                
                

                    
InChI

                    
InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H23ClN2

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A tricyclic antidepressant with particularly strong serotonin-reuptake inhibition, making it the most effective pharmacological treatment for obsessive-compulsive disorder. It also has uses in treating depression, panic disorder, and chronic pain.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Clomipramine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL415.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2801.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.