Dabigatran Etexilate Mesylate
A mesylate salt form of dabigatran etexilate used as an oral anticoagulant to prevent strokes and blood clots in patients with atrial fibrillation. Like other forms of dabigatran, it works by directly inhibiting thrombin to reduce clotting.
Khối lượng phân tử
723,8000 g/mol
TPSA
214,00 Ų
Lĩnh vực điều trị
Cơ chế tác dụng
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCCCCCOC(=O)NC(=N)c1ccc(NCc2nc3cc(C(=O)N(CCC(=O)OCC)c4ccccn4)ccc3n2C)cc1.CS(=O)(=O)O
InChI
InChI=1S/C34H41N7O5.CH4O3S/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43)41(20-18-31(42)45-5-2)29-11-8-9-19-36-29;1-5(2,3)4/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44);1H3,(H,2,3,4)
Molecular Formula
C35H45N7O8S
HBD / HBA
4 / 12
Liên kết có thể quay
18
Nguyên tử nặng
51
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
A mesylate salt form of dabigatran etexilate used as an oral anticoagulant to prevent strokes and blood clots in patients with atrial fibrillation. Like other forms of dabigatran, it works by directly inhibiting thrombin to reduce clotting.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Dabigatran Etexilate Mesylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1615369. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 135566083. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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