Dequalinium Chloride

CHEMBL121663 Phase 4 Đã phê duyệt Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
527.6 g/mol
LogP
Phase
4

The chloride salt of dequalinium, a topical antiseptic agent used in throat lozenges for oral infections and vaginal tablets for bacterial vaginosis. Its bisquaternary ammonium structure disrupts the membranes of bacteria, fungi, and protozoa.

Khối lượng phân tử

527,6000 g/mol

TPSA

59,80 Ų

Cơ chế tác dụng

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Cấu trúc 2D

SVG PNG

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SMILES

Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21.[Cl-].[Cl-]

InChI

InChI=1S/C30H38N4.2ClH/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34;;/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3;2*1H

Molecular Formula

C30H40Cl2N4

HBD / HBA

2 / 4

Liên kết có thể quay

11

Nguyên tử nặng

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

The chloride salt of dequalinium, a topical antiseptic agent used in throat lozenges for oral infections and vaginal tablets for bacterial vaginosis. Its bisquaternary ammonium structure disrupts the membranes of bacteria, fungi, and protozoa.

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Yes, Dequalinium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL121663. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 10649. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.