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Dexfenfluramine

CHEMBL248702 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
231.3 g/mol
LogP
3.4
Phase
4

The dextro-isomer of fenfluramine, an appetite suppressant that increases serotonin levels in the brain and was used for short-term weight management in obesity. It was withdrawn from the market in 1997 due to serious risks of heart valve damage and primary pulmonary hypertension. It is no longer available.

Khối lượng phân tử

231,2600 g/mol

LogP

3,40

TPSA

12,00 Ų

Lipinski RO5

Đạt

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCN[C@@H](C)Cc1cccc(C(F)(F)F)c1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H16F3N

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
16

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
The dextro-isomer of fenfluramine, an appetite suppressant that increases serotonin levels in the brain and was used for short-term weight management in obesity. It was withdrawn from the market in 1997 due to serious risks of heart valve damage and primary pulmonary hypertension. It is no longer available.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Dexfenfluramine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL248702.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 66265.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.