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Diatrizoate Sodium

CHEMBL1200581 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
635.9 g/mol
LogP
—
Phase
4

A sodium salt of the iodinated contrast agent diatrizoate, used in radiological imaging procedures such as urography, venography, and CT scans to make blood vessels, organs, and body cavities visible on X-ray images. The iodine atoms absorb X-rays, creating contrast between structures. It can cause allergic reactions and kidney damage, particularly in patients with existing kidney problems.

Khối lượng phân tử

635,8900 g/mol

TPSA

98,30 Ų

Lĩnh vực điều trị

Inflammatory Bowel Disease Colorectal Cancer

Cơ chế tác dụng

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)[O-])c1I.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C11H9I3N2O4.Na/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;/h1-2H3,(H,15,17)(H,16,18)(H,19,20);/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H8I3N2NaO4

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
3

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
21

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A sodium salt of the iodinated contrast agent diatrizoate, used in radiological imaging procedures such as urography, venography, and CT scans to make blood vessels, organs, and body cavities visible on X-ray images. The iodine atoms absorb X-rays, creating contrast between structures. It can cause allergic reactions and kidney damage, particularly in patients with existing kidney problems.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Diatrizoate Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200581.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23672589.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.