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Dipyridamole

CHEMBL932 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
504.6 g/mol
LogP
0.7
Phase
4

A medication that inhibits platelet aggregation and causes vasodilation, used in combination with aspirin to prevent stroke in patients with non-cardioembolic TIA or ischemic stroke, and intravenously as part of cardiac stress testing (pharmacological stress echocardiography or nuclear imaging). It works by inhibiting the phosphodiesterase enzyme that breaks down cyclic AMP. Headache is a very common side effect.

Khối lượng phân tử

504,6000 g/mol

LogP

0,70

TPSA

145,00 Ų

Lipinski RO5

Không đạt

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Cardiovascular Disease Rheumatoid Arthritis Migraine Schizophrenia Systemic Lupus Erythematosus Stroke Deep Vein Thrombosis / Pulmonary Embolism Type 2 Diabetes Hypertension Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)nc(N3CCCCC3)c2n1

                

                

                
                

                    
InChI

                    
InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H40N8O4

                    

                    
                    

                        
HBD / HBA

                        
4 / 12

                    

                    
                    

                        
Liên kết có thể quay

                        
12

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
36

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A medication that inhibits platelet aggregation and causes vasodilation, used in combination with aspirin to prevent stroke in patients with non-cardioembolic TIA or ischemic stroke, and intravenously as part of cardiac stress testing (pharmacological stress echocardiography or nuclear imaging). It works by inhibiting the phosphodiesterase enzyme that breaks down cyclic AMP. Headache is a very common side effect.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Dipyridamole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL932.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3108.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.