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Florbetapir F 18

CHEMBL1774461 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
359.4 g/mol
LogP
3.5
Phase
4

This radioactive imaging agent binds to beta-amyloid plaques in the brain and is used with PET scanning to help diagnose Alzheimer's disease. It provides visual information about amyloid burden that can support clinical evaluation in patients with cognitive impairment.

Khối lượng phân tử

359,4000 g/mol

LogP

3,50

TPSA

52,60 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Alzheimer's Disease Parkinson's Disease Multiple Sclerosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CNc1ccc(/C=C/c2ccc(OCCOCCOCC[18F])nc2)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H25FN2O3

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
Liên kết có thể quay

                        
12

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
26

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This radioactive imaging agent binds to beta-amyloid plaques in the brain and is used with PET scanning to help diagnose Alzheimer's disease. It provides visual information about amyloid burden that can support clinical evaluation in patients with cognitive impairment.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Florbetapir F 18 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1774461.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 24822371.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.