Fluorodopa F 18
A radioactively labeled form of a dopamine precursor used in PET imaging to assess dopamine system function in the brain. It is primarily used to help diagnose Parkinson's disease by detecting areas of reduced dopamine production. This diagnostic agent provides critical information about disease severity and progression.
Khối lượng phân tử
214,1800 g/mol
LogP
-2,00
TPSA
104,00 Ų
Lipinski RO5
Đạt
Lĩnh vực điều trị
Cơ chế tác dụng
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
N[C@@H](Cc1cc(O)c(O)cc1[18F])C(=O)O
InChI
InChI=1S/C9H10FNO4/c10-5-3-8(13)7(12)2-4(5)1-6(11)9(14)15/h2-3,6,12-13H,1,11H2,(H,14,15)/t6-/m0/s1/i10-1
Molecular Formula
C9H10FNO4
HBD / HBA
4 / 6
Liên kết có thể quay
3
Nguyên tử nặng
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
A radioactively labeled form of a dopamine precursor used in PET imaging to assess dopamine system function in the brain. It is primarily used to help diagnose Parkinson's disease by detecting areas of reduced dopamine production. This diagnostic agent provides critical information about disease severity and progression.
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Yes, Fluorodopa F 18 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3400972. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 56494. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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