Gadofosveset Trisodium

CHEMBL1908362 Phase 4 Đã phê duyệt Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
957.9 g/mol
LogP
Phase
4

This gadolinium-based contrast agent binds to albumin in the blood, giving it a prolonged blood pool residence time ideal for MR angiography imaging of blood vessels. It allows visualization of arterial and venous structures with high resolution over an extended imaging window.

Khối lượng phân tử

957,9000 g/mol

TPSA

269,00 Ų

Lĩnh vực điều trị

Cơ chế tác dụng

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Cấu trúc 2D

SVG PNG

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SMILES

C1CC(CCC1OP(=O)([O-])OCC(CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-])(C2=CC=CC=C2)C3=CC=CC=C3.[Na+].[Na+].[Na+].[Gd+3]

InChI

InChI=1S/C33H44N3O14P.Gd.3Na/c37-28(38)18-34(15-16-35(19-29(39)40)20-30(41)42)17-26(36(21-31(43)44)22-32(45)46)23-49-51(47,48)50-27-11-13-33(14-12-27,24-7-3-1-4-8-24)25-9-5-2-6-10-25;;;;/h1-10,26-27H,11-23H2,(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H,45,46)(H,47,48);;;;/q;+3;3*+1/p-6

Molecular Formula

C33H38GdN3Na3O14P

HBD / HBA

- / 17

Liên kết có thể quay

18

Nguyên tử nặng

55

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

This gadolinium-based contrast agent binds to albumin in the blood, giving it a prolonged blood pool residence time ideal for MR angiography imaging of blood vessels. It allows visualization of arterial and venous structures with high resolution over an extended imaging window.

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Yes, Gadofosveset Trisodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1908362. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 73049652. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.