Iobenguane I 131
This radioiodine-131 labeled compound is used as a targeted radiotherapy agent for inoperable pheochromocytoma and paraganglioma, rare tumors of the adrenal gland and related tissue. It accumulates specifically in these norepinephrine-producing tumors, delivering localized beta radiation to destroy cancer cells. It can also be used for imaging before deciding on therapy.
Khối lượng phân tử
279,0900 g/mol
LogP
1,00
TPSA
64,40 Ų
Lipinski RO5
Đạt
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
N=C(N)NCc1cccc([131I])c1
InChI
InChI=1S/C8H10IN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)/i9+4
Molecular Formula
C8H10IN3
HBD / HBA
2 / 1
Liên kết có thể quay
2
Nguyên tử nặng
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
This radioiodine-131 labeled compound is used as a targeted radiotherapy agent for inoperable pheochromocytoma and paraganglioma, rare tumors of the adrenal gland and related tissue. It accumulates specifically in these norepinephrine-producing tumors, delivering localized beta radiation to destroy cancer cells. It can also be used for imaging before deciding on therapy.
Yes, Iobenguane I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1615779. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71184. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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