Iopanoic Acid
This oral iodinated compound was used as a contrast agent for cholecystography to visualize the gallbladder on X-ray. After ingestion, it was absorbed and concentrated in bile, making the gallbladder and any stones visible. It is also known to inhibit thyroid hormone metabolism and was historically used to manage thyrotoxicosis.
Khối lượng phân tử
570,9300 g/mol
LogP
3,90
TPSA
63,30 Ų
Lipinski RO5
Đạt
Cơ chế tác dụng
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCC(Cc1c(I)cc(I)c(N)c1I)C(=O)O
InChI
InChI=1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)
Molecular Formula
C11H12I3NO2
HBD / HBA
2 / 3
Liên kết có thể quay
4
Nguyên tử nặng
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
This oral iodinated compound was used as a contrast agent for cholecystography to visualize the gallbladder on X-ray. After ingestion, it was absorbed and concentrated in bile, making the gallbladder and any stones visible. It is also known to inhibit thyroid hormone metabolism and was historically used to manage thyrotoxicosis.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Iopanoic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL867. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3735. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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