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Malathion

CHEMBL1200468 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
330.4 g/mol
LogP
2.4
Phase
4

An organophosphate compound used medically as a topical treatment for head lice infestations, working by inhibiting acetylcholinesterase in the lice's nervous system to kill both adult lice and their eggs. It is applied directly to dry hair, left for a set period, and then washed out, usually requiring a repeat application after about a week.

Khối lượng phân tử

330,4000 g/mol

LogP

2,40

TPSA

128,00 Ų

Lipinski RO5

Đạt

Cơ chế tác dụng

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC

                

                

                
                

                    
InChI

                    
InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H19O6PS2

                    

                    
                    

                        
HBD / HBA

                        
- / 8

                    

                    
                    

                        
Liên kết có thể quay

                        
11

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
An organophosphate compound used medically as a topical treatment for head lice infestations, working by inhibiting acetylcholinesterase in the lice's nervous system to kill both adult lice and their eggs. It is applied directly to dry hair, left for a set period, and then washed out, usually requiring a repeat application after about a week.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Malathion is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200468.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4004.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.