Methsuximide
An anticonvulsant medication used to control absence seizures (brief lapses of consciousness) in patients with epilepsy who have not responded to other seizure medications. It works by reducing abnormal electrical activity in the brain.
Khối lượng phân tử
203,2400 g/mol
LogP
1,20
TPSA
37,40 Ų
Lipinski RO5
Đạt
Lĩnh vực điều trị
Cơ chế tác dụng
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CN1C(=O)CC(C)(c2ccccc2)C1=O
InChI
InChI=1S/C12H13NO2/c1-12(9-6-4-3-5-7-9)8-10(14)13(2)11(12)15/h3-7H,8H2,1-2H3
Molecular Formula
C12H13NO2
HBD / HBA
- / 2
Liên kết có thể quay
1
Nguyên tử nặng
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
An anticonvulsant medication used to control absence seizures (brief lapses of consciousness) in patients with epilepsy who have not responded to other seizure medications. It works by reducing abnormal electrical activity in the brain.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Methsuximide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL697. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6476. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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