Nalbuphine Hydrochloride

CHEMBL1201132 Phase 4 Đã phê duyệt Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

393.9 g/mol

LogP

—

Phase

4

This is the hydrochloride salt form of nalbuphine used for the same pain management indications.

Khối lượng phân tử

393,9000 g/mol

TPSA

73,20 Å²

Lĩnh vực điều trị

Pain Management Non-Small Cell Lung Cancer Asthma Generalized Anxiety Disorder Insomnia Obesity Hypertension Breast Cancer Chronic Pain Heart Failure Leukemia

Cơ chế tác dụng

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

Cấu trúc 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

Cl.Oc1ccc2c3c1O[C@H]1[C@@H](O)CC[C@@]4(O)[C@@H](C2)N(CC2CCC2)CC[C@]314

InChI

InChI=1S/C21H27NO4.ClH/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H/t15-,16+,19-,20-,21+;/m0./s1

Molecular Formula

C21H28ClNO4

HBD / HBA

4 / 5

Liên kết có thể quay

2

Nguyên tử nặng

27

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

This is the hydrochloride salt form of nalbuphine used for the same pain management indications.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Nalbuphine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201132. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5360733. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Cấu trúc

Dữ liệu nhanh

Công thức: C21H28ClNO4

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Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.