Phenacemide
Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.
Khối lượng phân tử
178,1900 g/mol
LogP
0,90
TPSA
72,20 Ų
Lipinski RO5
Đạt
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
NC(=O)NC(=O)Cc1ccccc1
InChI
InChI=1S/C9H10N2O2/c10-9(13)11-8(12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,10,11,12,13)
Molecular Formula
C9H10N2O2
HBD / HBA
2 / 2
Liên kết có thể quay
2
Nguyên tử nặng
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.
Yes, Phenacemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL918. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4753. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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