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Pyridoxine

CHEMBL1364 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
169.2 g/mol
LogP
-0.8
Phase
4

Pyridoxine (vitamin B6) is a water-soluble vitamin that is converted to its active coenzyme forms pyridoxal-5-phosphate (PLP) and pyridoxamine-5-phosphate, which serve as essential cofactors for over 100 enzymatic reactions in amino acid metabolism, neurotransmitter synthesis, and glycogen catabolism. It is used therapeutically for pyridoxine deficiency states, isoniazid-induced neuropathy, pyridoxine-dependent epilepsy, and nausea of pregnancy.

Khối lượng phân tử

169,1800 g/mol

LogP

-0,80

TPSA

73,60 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Glaucoma Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Generalized Anxiety Disorder Inflammatory Bowel Disease Psoriasis Systemic Lupus Erythematosus Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Oncology Stroke Deep Vein Thrombosis / Pulmonary Embolism Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Malaria HIV/AIDS Tuberculosis Heart Failure Atrial Fibrillation Cardiovascular Disease Prostate Cancer Colorectal Cancer

Cơ chế tác dụng

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1ncc(CO)c(CO)c1O

                

                

                
                

                    
InChI

                    
InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H11NO3

                    

                    
                    

                        
HBD / HBA

                        
3 / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
2

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
12

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Pyridoxine (vitamin B6) is a water-soluble vitamin that is converted to its active coenzyme forms pyridoxal-5-phosphate (PLP) and pyridoxamine-5-phosphate, which serve as essential cofactors for over 100 enzymatic reactions in amino acid metabolism, neurotransmitter synthesis, and glycogen catabolism. It is used therapeutically for pyridoxine deficiency states, isoniazid-induced neuropathy, pyridoxine-dependent epilepsy, and nausea of pregnancy.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Pyridoxine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1364.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 1054.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.