Reteplase
Reteplase is a recombinant deletion mutant of tissue plasminogen activator (tPA) that binds fibrin in thrombi and catalyzes the conversion of plasminogen to plasmin, which lyses fibrin clots and restores blood flow in occluded vessels. It is approved for the treatment of acute myocardial infarction and is used for management of massive pulmonary embolism and acute ischemic stroke.
Lĩnh vực điều trị
Cơ chế tác dụng
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Reteplase is a recombinant deletion mutant of tissue plasminogen activator (tPA) that binds fibrin in thrombi and catalyzes the conversion of plasminogen to plasmin, which lyses fibrin clots and restores blood flow in occluded vessels. It is approved for the treatment of acute myocardial infarction and is used for management of massive pulmonary embolism and acute ischemic stroke.
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
Yes, Reteplase is an approved drug. It has reached clinical phase 4. It is classified as a Enzyme.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107885. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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