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Sodium Tetradecyl Sulfate

CHEMBL1200354 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
316.4 g/mol
LogP
—
Phase
4

Sodium tetradecyl sulfate is a detergent-class sclerosing agent used for the treatment of varicose veins and hemorrhoids by injecting directly into the vessel lumen, causing endothelial damage, thrombosis, and subsequent fibrosis to obliterate the vein. By disrupting the endothelial cell lipid bilayer, it triggers an inflammatory response leading to sclerosis and permanent closure of the target vessel. It is used in sclerotherapy as an alternative to surgical vein stripping.

Khối lượng phân tử

316,4300 g/mol

TPSA

74,80 Ų

Lĩnh vực điều trị

Pain Management Chronic Pain

Cơ chế tác dụng

Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)[O-].[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C14H30O4S.Na/c1-5-7-8-13(6-2)9-10-14(11-12(3)4)18-19(15,16)17;/h12-14H,5-11H2,1-4H3,(H,15,16,17);/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C14H29NaO4S

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
11

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Sodium tetradecyl sulfate is a detergent-class sclerosing agent used for the treatment of varicose veins and hemorrhoids by injecting directly into the vessel lumen, causing endothelial damage, thrombosis, and subsequent fibrosis to obliterate the vein. By disrupting the endothelial cell lipid bilayer, it triggers an inflammatory response leading to sclerosis and permanent closure of the target vessel. It is used in sclerotherapy as an alternative to surgical vein stripping.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sodium Tetradecyl Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200354.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23665772.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.