Somatropin
Somatropin is recombinant human growth hormone (hGH) with an identical amino acid sequence to pituitary-derived GH, used for treatment of growth hormone deficiency in children and adults, Turner syndrome, Prader-Willi syndrome, chronic kidney disease-associated short stature, and other growth disorders. It binds to GH receptors on target tissues, activating the JAK2-STAT5 signaling pathway to stimulate IGF-1 synthesis, linear bone growth, muscle anabolism, and lipolysis. Multiple delivery systems are available including daily subcutaneous injection devices.
Lĩnh vực điều trị
Cơ chế tác dụng
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Somatropin is recombinant human growth hormone (hGH) with an identical amino acid sequence to pituitary-derived GH, used for treatment of growth hormone deficiency in children and adults, Turner syndrome, Prader-Willi syndrome, chronic kidney disease-associated short stature, and other growth disorders. It binds to GH receptors on target tissues, activating the JAK2-STAT5 signaling pathway to stimulate IGF-1 synthesis, linear bone growth, muscle anabolism, and lipolysis. Multiple delivery systems are available including daily subcutaneous injection devices.
As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.
Yes, Somatropin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201621. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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