Sulfamethoxazole
Combined with trimethoprim (as co-trimoxazole), this sulfonamide antibiotic blocks two sequential steps in bacterial folate synthesis, making the combination highly effective against a wide range of bacterial and protozoal infections. It is a first-line treatment for urinary tract infections, Pneumocystis pneumonia in immunocompromised patients, and several other conditions.
Khối lượng phân tử
253,2800 g/mol
LogP
0,90
TPSA
107,00 Ų
Lipinski RO5
Đạt
Lĩnh vực điều trị
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI
InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
Molecular Formula
C10H11N3O3S
HBD / HBA
2 / 6
Liên kết có thể quay
3
Nguyên tử nặng
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Combined with trimethoprim (as co-trimoxazole), this sulfonamide antibiotic blocks two sequential steps in bacterial folate synthesis, making the combination highly effective against a wide range of bacterial and protozoal infections. It is a first-line treatment for urinary tract infections, Pneumocystis pneumonia in immunocompromised patients, and several other conditions.
Yes, Sulfamethoxazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL443. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5329. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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