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Talc

CHEMBL3989756 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
379.3 g/mol
LogP
—
Phase
4

Talc is a hydrated magnesium silicate mineral used medically as a pleurodesis agent, where it is instilled into the pleural space to cause inflammation and adhesion, preventing recurrent pleural effusions. It also serves as an inactive excipient and lubricant in pharmaceutical tablet and powder formulations. Its primary therapeutic application is in managing malignant pleural effusions associated with conditions such as lung cancer.

Khối lượng phân tử

379,2700 g/mol

TPSA

150,00 Ų

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Respiratory Disease Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Migraine Generalized Anxiety Disorder Oncology Multiple Sclerosis Non-Alcoholic Fatty Liver Disease Hyperlipidemia Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer HIV/AIDS Hepatitis C Prostate Cancer Colorectal Cancer Leukemia

Cơ chế tác dụng

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O.O=[Mg].O=[Mg].O=[Mg].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O

                

                

                
                

                    
InChI

                    
InChI=1S/3Mg.4O2Si.H2O.3O/c;;;4*1-3-2;;;;/h;;;;;;;1H2;;;

                

                

                

                    
                    

                        
Molecular Formula

                        
H2Mg3O12Si4

                    

                    
                    

                        
HBD / HBA

                        
2 / 12

                    

                    
                    

                        
Liên kết có thể quay

                        
0

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Talc is a hydrated magnesium silicate mineral used medically as a pleurodesis agent, where it is instilled into the pleural space to cause inflammation and adhesion, preventing recurrent pleural effusions. It also serves as an inactive excipient and lubricant in pharmaceutical tablet and powder formulations. Its primary therapeutic application is in managing malignant pleural effusions associated with conditions such as lung cancer.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Talc is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3989756.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 165411828.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.