💊 Thuốc A-Z 🧬 Đích tác dụng 🛠 Công cụ 📚 Hướng dẫn
Tất cả thuốc Phân loại thuốc Lĩnh vực điều trị Tác dụng phụ
Hướng dẫn Từ điển thuật ngữ Dòng thời gian
So sánh Hành trình của thuốc Các họ thuốc
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Technetium (99Mtc) Apcitide

CHEMBL1201524 Phase 4 Đã phê duyệt Protein
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
1525.5 g/mol
LogP
—
Phase
4

Technetium (99mTc) apcitide is a radiolabeled synthetic peptide that binds to the glycoprotein IIb/IIIa (αIIbβ3) receptor on activated platelets, enabling scintigraphic imaging of acute venous thrombosis. The technetium-99m radiolabel emits gamma radiation detectable by a gamma camera, allowing non-invasive localization of thrombi in the deep veins. It represents a targeted nuclear medicine imaging approach for thrombus detection.

Khối lượng phân tử

1525,5000 g/mol

TPSA

688,00 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

SMILES

CC(=O)NCSC[C@@H](C(=O)NCC(=O)N[C@@H](CSCNC(=O)C)C(=NCC(=NCC(=N[C@@H](C[S-])C(=O)N)[O-])[O-])[O-])NC(=O)CNC(=O)CNC(=O)[C@@H]1CSCC(=O)N[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N1)CC(=O)[O-])CSCCCN)CC2=CC=C(C=C2)O.[O-2].[Na+].[99Tc+5]

InChI

InChI=1S/C51H77N17O19S5.Na.O.Tc/c1-26(69)60-24-91-21-33(46(82)56-12-37(72)54-14-39(74)64-32(18-88)45(53)81)66-42(77)17-58-47(83)34(22-92-25-61-27(2)70)65-40(75)15-55-38(73)13-57-49(85)36-20-90-23-43(78)63-30(10-28-4-6-29(71)7-5-28)50(86)67-35(19-89-9-3-8-52)48(84)59-16-41(76)62-31(11-44(79)80)51(87)68-36;;;/h4-7,30-36,71,88H,3,8-25,52H2,1-2H3,(H2,53,81)(H,54,72)(H,55,73)(H,56,82)(H,57,85)(H,58,83)(H,59,84)(H,60,69)(H,61,70)(H,62,76)(H,63,78)(H,64,74)(H,65,75)(H,66,77)(H,67,86)(H,68,87)(H,79,80);;;/q;+1;-2;+5/p-5/t30-,31+,32+,33+,34+,35+,36+;;;/m1.../s1/i;;;1+1

Molecular Formula

C51H72N17NaO20S5Tc-

HBD / HBA

15 / 29

Liên kết có thể quay

34

Nguyên tử nặng

95

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

Technetium (99mTc) apcitide is a radiolabeled synthetic peptide that binds to the glycoprotein IIb/IIIa (αIIbβ3) receptor on activated platelets, enabling scintigraphic imaging of acute venous thrombosis. The technetium-99m radiolabel emits gamma radiation detectable by a gamma camera, allowing non-invasive localization of thrombi in the deep veins. It represents a targeted nuclear medicine imaging approach for thrombus detection.

Yes, Technetium (99Mtc) Apcitide is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201524. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 72941734. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.