Technetium Tc 99M Sulfur Colloid
Technetium Tc 99m sulfur colloid is a radiolabeled colloidal particle preparation that is phagocytosed by reticuloendothelial cells (Kupffer cells in the liver, spleen, and bone marrow), used for liver-spleen scintigraphy, bone marrow imaging, and sentinel lymph node mapping in breast cancer and melanoma. The particle size determines the biodistribution: larger particles concentrate in the liver and spleen, while filtered smaller particles enable gastrointestinal transit and lymphoscintigraphy. It is widely used for sentinel node biopsy guidance in surgical oncology.
Khối lượng phân tử
355,4000 g/mol
TPSA
202,00 Ų
Lĩnh vực điều trị
Pharmacokinetics (PK)
Pharmacodynamics (PD)
SMILES
S1SSSSSSS1.[99Tc]
InChI
InChI=1S/S8.Tc/c1-2-4-6-8-7-5-3-1;/i;1+1
Molecular Formula
S8Tc
HBD / HBA
- / 8
Liên kết có thể quay
0
Nguyên tử nặng
9
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Technetium Tc 99m sulfur colloid is a radiolabeled colloidal particle preparation that is phagocytosed by reticuloendothelial cells (Kupffer cells in the liver, spleen, and bone marrow), used for liver-spleen scintigraphy, bone marrow imaging, and sentinel lymph node mapping in breast cancer and melanoma. The particle size determines the biodistribution: larger particles concentrate in the liver and spleen, while filtered smaller particles enable gastrointestinal transit and lymphoscintigraphy. It is widely used for sentinel node biopsy guidance in surgical oncology.
Yes, Technetium Tc 99M Sulfur Colloid is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201529. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 76957057. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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