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Teriflunomide

CHEMBL973 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
270.2 g/mol
LogP
3.3
Phase
4

This oral medication is used to reduce the frequency of relapses and slow the progression of relapsing forms of multiple sclerosis (MS). It works by blocking an enzyme needed for the production of immune cells that attack the myelin sheath around nerves. Women of childbearing age must use reliable contraception during treatment due to the risk of serious birth defects.

Khối lượng phân tử

270,2100 g/mol

LogP

3,30

TPSA

73,10 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Melanoma Multiple Sclerosis Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C/C(O)=C(\C#N)C(=O)Nc1ccc(C(F)(F)F)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H9F3N2O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 6

                    

                    
                    

                        
Liên kết có thể quay

                        
2

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This oral medication is used to reduce the frequency of relapses and slow the progression of relapsing forms of multiple sclerosis (MS). It works by blocking an enzyme needed for the production of immune cells that attack the myelin sheath around nerves. Women of childbearing age must use reliable contraception during treatment due to the risk of serious birth defects.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Teriflunomide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL973.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 54684141.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.