Treprostinil Diolamine

CHEMBL2107815 Phase 4 Đã phê duyệt Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

495.6 g/mol

LogP

—

Phase

4

Treprostinil diolamine is the diolamine salt form of treprostinil, a prostacyclin receptor agonist used for pulmonary arterial hypertension. See treprostinil for complete pharmacological details. This salt formulation is used in oral extended-release tablet preparations for PAH management in heart failure and hypertension contexts.

Khối lượng phân tử

495,6000 g/mol

TPSA

139,00 Å²

Lĩnh vực điều trị

Hypertension Heart Failure

Cơ chế tác dụng

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Cấu trúc 2D

SVG PNG

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SMILES

CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)O)c3C[C@H]2C[C@H]1O.OCCNCCO

InChI

InChI=1S/C23H34O5.C4H11NO2/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;6-3-1-5-2-4-7/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);5-7H,1-4H2/t16-,17-,18+,19-,21+;/m0./s1

Molecular Formula

C27H45NO7

HBD / HBA

6 / 8

Liên kết có thể quay

14

Nguyên tử nặng

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

Treprostinil diolamine is the diolamine salt form of treprostinil, a prostacyclin receptor agonist used for pulmonary arterial hypertension. See treprostinil for complete pharmacological details. This salt formulation is used in oral extended-release tablet preparations for PAH management in heart failure and hypertension contexts.

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Yes, Treprostinil Diolamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107815. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 11179459. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Cấu trúc

Dữ liệu nhanh

Công thức: C27H45NO7

Liên kết ngoài

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Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Treprostinil Diolamine

Lĩnh vực điều trị

Cơ chế tác dụng

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

Câu hỏi thường gặp

References & Data Sources

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