Trientine Tetrahydrochloride
Trientine tetrahydrochloride is the tetrahydrochloride salt form of trientine (triethylenetetramine), providing a more stable and water-soluble formulation of the copper-chelating agent used in Wilson's disease. See trientine for complete pharmacological details. This salt form has been developed as an alternative formulation to address stability issues with previous trientine preparations.
Khối lượng phân tử
292,1000 g/mol
TPSA
76,10 Ų
Cơ chế tác dụng
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
Cl.Cl.Cl.Cl.NCCNCCNCCN
InChI
InChI=1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H
Molecular Formula
C6H22Cl4N4
HBD / HBA
8 / 4
Liên kết có thể quay
7
Nguyên tử nặng
14
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Trientine tetrahydrochloride is the tetrahydrochloride salt form of trientine (triethylenetetramine), providing a more stable and water-soluble formulation of the copper-chelating agent used in Wilson's disease. See trientine for complete pharmacological details. This salt form has been developed as an alternative formulation to address stability issues with previous trientine preparations.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Trientine Tetrahydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5095420. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71434. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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