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Triglycerides, Medium-Chain

CHEMBL2108659 Phase 4 Đã phê duyệt Unknown
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
387.5 g/mol
LogP
6.0
Phase
4

Medium-chain triglycerides (MCTs) are glycerol esters of medium-chain fatty acids (C6-C12, primarily caprylic C8 and capric C10 acids) that are hydrolyzed and absorbed more rapidly than long-chain triglycerides, entering portal circulation directly without requiring chylomicron formation and undergoing preferential hepatic beta-oxidation to produce ketone bodies. They are used as nutritional supplements and medical foods in malabsorption syndromes, ketogenic diet therapy for refractory epilepsy, and MCT-based formulas for patients with impaired fat digestion. Their rapid conversion to ketones has also generated interest in Alzheimer's disease research as an alternative brain energy substrate.

Khối lượng phân tử

387,5000 g/mol

LogP

6,00

TPSA

107,00 Ų

Lipinski RO5

Đạt

Pharmacokinetics (PK)

Pharmacodynamics (PD)

SMILES

CCCCCCC(CCCCCCCCCC(=O)[O-])C(=O)OCC(CO)O

InChI

InChI=1S/C21H40O6/c1-2-3-4-10-13-18(21(26)27-17-19(23)16-22)14-11-8-6-5-7-9-12-15-20(24)25/h18-19,22-23H,2-17H2,1H3,(H,24,25)/p-1

Molecular Formula

C21H39O6-

HBD / HBA

2 / 6

Liên kết có thể quay

19

Nguyên tử nặng

27

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

Medium-chain triglycerides (MCTs) are glycerol esters of medium-chain fatty acids (C6-C12, primarily caprylic C8 and capric C10 acids) that are hydrolyzed and absorbed more rapidly than long-chain triglycerides, entering portal circulation directly without requiring chylomicron formation and undergoing preferential hepatic beta-oxidation to produce ketone bodies. They are used as nutritional supplements and medical foods in malabsorption syndromes, ketogenic diet therapy for refractory epilepsy, and MCT-based formulas for patients with impaired fat digestion. Their rapid conversion to ketones has also generated …

Yes, Triglycerides, Medium-Chain is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2108659. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 91757308. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.